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We are currently developing novel DNA editing technologies to broaden the scope of genome engineering. Our strategy is based on identifyi...
The reproductive organs of the female body have long been a site of contention, where opposing ideologies in religion, politics, and cult...
The continuous monitoring of physical patterns such as viscoelasticity and pH in the immediate environment of tissues is vitally importan...
Nearly all classes of wearable and implantable biomedical devices depend on battery power for continuous operation. However, the life spa...
Today’s health sensors (which monitor breathing, heartbeats, steps, etc.) require their users to wear them on their bodies. In contrast, ...
Lower-extremity amputation surgery has not seen significant change since the Civil War. This research is focused on the development of no...
Brain circuits are large, 3D structures. However, the building blocks—proteins, signaling complexes, synapses—are or...
The gram-positive cocci Streptococcus pneumoniae causes pneumonia, otitis media, meningitis, and bacteremia in pediatric, elderly, and im...
Lyme disease is the most common vector-borne infection in North America. People are infected when bitten by ticks; ticks are typically in...
We collaborated with NIAS (National Institute of Agricultural Science) to genetically engineer silkworms to develop new kinds of silk for...
"Without urgent, coordinated action by many stakeholders, the world is headed for a post-antibiotic era, in which common infections and m...
The Synthetic Apiary proposes a new kind of environment, bridging urban and organismic scales by exploring one of the most important orga...
Recent advancements in orthopedic implants have made way for a new generation of bionic limbs that attach directly to the skeleton. Lever...
In the United States, there are an estimated 1.7 million people living with amputation, with that number expected to double by 2050. Comp...
We are providing our tools to the community, and also using them within our lab, to analyze how specific brain mechanisms (molecular, cel...
The brain is a three-dimensional, densely-wired circuit that computes via large sets of widely distributed neurons i...
We have pioneered the development of fully genetically encoded reagents that, when targeted to specific cells, enabl...
Recent advances in artificial limbs have resulted in the provision of powered ankle and knee function for lower extremity amputees and po...
New technologies for recording neural activity, controlling neural activity, or building brain circuits, may be capable some day of servi...
How will gene drive systems evolve once released into the wild? Can they be reliably overwritten and blocked by immunizing reversal drive...