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The brain is a three-dimensional, densely-wired circuit that computes via large sets of widely distributed neurons interacting at fast ti...
This project seeks to examine the effects of altered gravity on an individual’s physiology during parabolic flight. Specifically, we will...
Recent advancements in orthopedic implants have made way for a new generation of bionic limbs that attach directly to the skeleton. Lever...
Continuous localized tissue monitoring and disease treatmentThe ability to continuously monitor physical patterns, such as pH in the...
Two-dimensional radiographs are commonly used for evaluating sub-surface hard structures of teeth, but they have low sensitivity for earl...
Paper diagnostics can be used for affordable and scalable biomarker detection. We propose new methods for stabilizing cellulose-based imm...
"Without urgent, coordinated action by many stakeholders, the world is headed for a post-antibiotic era, in which common infections and m...
The development of biotechnologies since the era of recombinant DNA in the 1970s has occurred largely via the interaction of academic, in...
New technologies for recording neural activity, controlling neural activity, or building brain circuits, may be capable someday of servin...
We are providing our tools to the community, and also using them within our lab, to analyze how specific brain mechanisms (molecular, cel...
We have pioneered the development of fully genetically encoded reagents that, when targeted to specific cells, enable their physiology to...
Complex biological systems such as brain circuits are extended 3-D structures made out of nanoscale building blocks such as proteins, RNA...
Nearly all classes of wearable and implantable biomedical devices depend on battery power for continuous operation. However, the life spa...
This research track focuses on the use of computational (and experimental) techniques to understand the biomechanical behavior of human t...
Recent advances in medications for neurodegenerative disorders are expanding opportunities for improving the debilitating symptoms suffer...
Lyme disease is the most common vector-borne infection in North America. People are infected when bitten by ticks; ticks are typically in...
Lower-extremity amputation surgery has not seen significant change since the Civil War. This research is focused on the development of no...
Recent advances in artificial limbs have resulted in the provision of powered ankle and knee function for lower extremity amputees and po...
The Synthetic Apiary proposes a new kind of environment, bridging urban and organismic scales by exploring one of the most important orga...
Improvements in ingestible electronics with the capacity to sense physiological and pathophysiological states have transformed the standa...
We are currently developing novel DNA editing technologies to broaden the scope of genome engineering. Our strategy is based on identifyi...
Today’s health sensors (which monitor breathing, heartbeats, steps, etc.) require their users to wear them on their bodies. In contrast, ...
We collaborated with NIAS (National Institute of Agricultural Science) to genetically engineer silkworms to develop new kinds of silk for...
In the United States, there are an estimated 1.7 million people living with amputation, with that number expected to double by 2050. Comp...
How will gene drive systems evolve once released into the wild? Can they be reliably overwritten and blocked by immunizing reversal drive...