Allan Costa

Research Assistant

Groups

Molecular Machines

Allan dos Santos Costa is a PhD student at the Center for Bits and Atoms, Molecular Machines under Prof. Joseph Jacobson, and at the Atomic Architects group at the MIT RLE, co-advised by Prof. Tess Smidt.

His research is focused on biomolecular modeling and engineering through machine learning. He is particularly excited about structural problems and physics-inspired architectures, and about generative models for molecular design.

Project Research

Ophiuchus: Deep Neural Modeling of Protein Structures from First-Principles of Symmetry

We recently introduced Ophiuchus, a novel deep learning architecture for modeling protein structures. Ophiuchus is the first…

Thesis Research

Distillation of Language Model Semantics to Folded Three-Dimensional Protein Structures

Project Research

Rational Engineering of Proteins with Deep Learning

Designing protein inhibitors for a protein target using a combination of deep learning and high throughput wetlab screens.