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Space Exploration Initiative
Open Ocean
Sparking discussion about the social, cultural, and ethical implications of emerging technologies through design and storytelling
The widespread synthesis of common organic building blocks in space could have biased life beyond Earth towards chemical similarities to ...
Noah Jakimo, Pranam Chatterjee, Joseph M. Jacobson. Chimeric CRISPR guides enhance Cas9 target specificity, doi: https://doi.org/10.1101/147686
Engineering at the limits of complexity with molecular-scale parts
Lyme disease is the most common vector-borne infection in North America. People are infected when bitten by ticks; ticks are typically in...
Revealing insights into the human condition and repairing brain disorders via novel tools for mapping and fixing brain computations
The reproductive organs of the female body have long been a site of contention, where opposing ideologies in religion, politics, and cult...
Who should decide whether, when, and how to alter the environment? It's a hard question, especially when the decision will impact people ...
We are currently developing novel DNA editing technologies to broaden the scope of genome engineering. Our strategy is based on identifyi...
Exploring evolutionary and ecological engineering
Responsive Science is a way of conducting research that invites openness and community involvement from the earliest stages of each proje...
Residents are invited to weigh in on a plan to release genetically-modified mice on Nantucket to combat tick-borne diseases
Black-legged ticks in forests of the Northeast and Midwest have a variety of options for the three blood meals they consume in their life...
Pursue modular "daisy drive" platforms with the potential to safely, efficiently, and reversibly edit local sub-populations of organisms
Kevin Esvelt has emerged as a leader in the debate about the ethics and politics of releasing genetically engineered animals.
The initiative, working with George Church, professor of genetics at Harvard Medical School, and Kevin Esvelt, head of the Sculpting Evol...
Transdisciplinary artist Ani Liu spoke to us about her project as commentary on the state of reproductive rights today.
Kevin Esvelt leads the Sculpting Evolution Group at MIT. Their work explores “evolutionary and ecological engineering and responsive science
A transgenic chicken commercial for ovulating womenEsgtrogen Farms is a fictional company that raises genetically modified chickens that ...
We collaborated with NIAS (National Institute of Agricultural Science) to genetically engineer silkworms to develop new kinds of silk for...
Imagine you could edit a mouse’s genes to be resistant to Lyme Disease. The mouse would breed and evolution would take its course, leadin...
How will gene drive systems evolve once released into the wild? Can they be reliably overwritten and blocked by immunizing reversal drive...