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Research
Health 0.0

Health 0.0

#computer vision #human-computer interaction #architecture +26 more
Research
Space Exploration Initiative

Space Exploration Initiative

#robotics #design #virtual reality +56 more
Research
Open Ocean

Open Ocean

#robotics #virtual reality #art +31 more
Project Research

Self-Learning AI Model Learns from Patient Data to Design Novel Clinical Trials

Technical summaryUnstructured learning problems without well-defined rewards are unsuitable for current reinforcement learning (RL) appro...

in Health 0.0
Pratik Shah
#human-computer interaction #artificial intelligence #bioengineering +8 more
Project Research

Deep Learning to Develop and Analyze Computational Hematoxylin and Eosin Staining of Tissue Images for Digital Biopsies

Staining of tissues sections using chemical and biological dyes has been used for over a century for visualizing various tissue types and...

in Health 0.0
Pratik Shah
#human-computer interaction #artificial intelligence #bioengineering +8 more
Project Research

Artificial Intelligence and Machine Learning in Clinical Development: A Translational Perspective

Technical summary: Future of clinical development is on the verge of a major transformation due to convergence of large new digital data ...

in Health 0.0
Pratik Shah · Francis Kendall
#computer vision #human-computer interaction #artificial intelligence +10 more
Article Research

The ethical way to alter organisms

An inventor of CRISPR-based gene drive has some advice to improve science, ethics, and the life-saving potential of these technologies.

via The Boston Globe · Nov. 9, 2020
in Sculpting Evolution
#environment #genetics #health +3 more
Article Research

Episode 6: Reshaping nature through gene drives

Kevin Esvelt and other experts talk about the risks and possible benefits of using gene drives to eliminate diseases and invasive species.

via Brave New Planet podcast · Nov. 9, 2020
in Sculpting Evolution
#environment #genetics #health +3 more
Archived
Research
Design Fiction

Sparking discussion about the social, cultural, and ethical implications of emerging technologies through design and storytelling

#design #art #bioengineering +8 more
Not Accepting Applicants
Archived
Research
Synthetic Neurobiology

Revealing insights into the human condition and repairing brain disorders via novel tools for mapping and fixing brain computations

#art #artificial intelligence #bioengineering +24 more
Not Accepting Applicants
Post Research

MAS.S64. Real-world Evaluation of Artificial Intelligence and Genome Editing Technologies

MAS.S64 Real-world Evaluation of Artificial Intelligence and Genome Editing Technologies - Fall 2020 Online CourseWhen: Tuesdays, 3-...

Aug. 24, 2020
in Health 0.0
#artificial intelligence #genetics #social science +4 more
Research
Sculpting Evolution

Cultivating wisdom through evolutionary and ecological engineering

#agriculture #bioengineering #civic technology +23 more
Not Accepting Applicants
Research
Molecular Machines

Engineering at the limits of complexity with molecular-scale parts

#artificial intelligence #bioengineering #genetics +14 more
Accepting Applicants
Research
Center for Extreme Bionics

Center for Extreme Bionics

#robotics #bioengineering #genetics +14 more
Article Research

Nature-inspired CRISPR enzymes for expansive genome editing

Applied computational biology discoveries vastly expand the range of CRISPR’s access to DNA sequences.

via MIT News · May 19, 2020
in Molecular Machines
#bioengineering #genetics #alumni +1 more
Project Research

Robust Genome Editing with Broad Targeting CRISPR Enzymes

Programmable CRISPR enzymes are powerful and versatile tools for genome editing. They, however, require a specific protospacer adjacent m...

in Molecular Machines
Pranam Chatterjee · Noah Jakimo +1 more
#bioengineering #genetics #alumni +1 more
Article Research

Gene drives could stop the world's oldest problems. Kevin Esvelt wants to make sure they don't start any.

Esvelt's career has gone from straight science into ethics and safety.

via Inverse · April 1, 2020
in Sculpting Evolution
#environment #genetics #biology
Article Research

If you care about the future of Earth, you must care about the human species

How biologist Kevin Esvelt came to know the planet, in his own words.

via Inverse · April 1, 2020
in Sculpting Evolution
#environment #genetics #biology
Project Research

Ocean Cultures

The Māori of Aotearoa (New Zealand) have a long and deep connection to their island and ocean ecosystem. Concepts such as ...

in Open Ocean
Avery Normandin · Devora Najjar
#developing countries #environment #genetics +2 more
Post Research

Daisy drive: A local, open, and community-responsive approach to solving ecological problems

Pursue modular "daisy drive" platforms with the potential to safely, efficiently, and reversibly edit local sub-populations of organisms

July 19, 2017
in Sculpting Evolution
#genetics
Project Research

Gene Editing and Biomedical Ethics

This work is being continued through The Dalai Lama Center for Ethics and Transformative Values at MIT.The initiative, working ...

in Ethics
Kevin Esvelt · Tenzin Priyadarshi
#genetics #ethics
Archived
Article Research

Is biohacking ethical? It’s complicated. A new Netflix series explains why.

Unnatural Selection tackles tough questions about CRISPR gene editing, designer babies, and more.

via Vox · Oct. 24, 2019
in Sculpting Evolution
#genetics #ethics #technology
Article Research

This gene technology could change the world. Its maker isn’t sure it should.

How does one scientist deal with the potential ramifications of his own creation?

via Vice · Nov. 18, 2019
in Sculpting Evolution
#environment #genetics #health +1 more
Article Research

In-cell sequencing reveals genome’s natural geometry

A new method for sequencing the genome of an intact single cell may help researchers understand how key autism genes are regulated.

via Spectrum News · Oct. 23, 2019
in Synthetic Neurobiology
#genetics #neurobiology #technology
Project Research

Mice Against Ticks - Preventing tick-borne disease by permanently immunizing mice

Lyme disease is the most common vector-borne infection in North America. People are infected when bitten by ticks; ticks are typically in...

in Sculpting Evolution
Kevin Esvelt · Joanna Buchthal
#agriculture #bioengineering #crowdsourcing +9 more
Article Research

Ticks: They’re not just for hikers anymore

The menacing mites have invaded suburban backyards and even parts of Boston. And Lyme disease isn’t the only thing they carry.

via The Boston Globe · Aug. 23, 2019
in Sculpting Evolution
#genetics #health #wellbeing
Article Research

A community-guided genome editing project can fight Lyme disease

Kevin Esvelt writes about the Sculpting Evolution group’s project to immunize mice against Lyme disease through gene editing.

via STAT · Aug. 22, 2019
in Sculpting Evolution
#genetics #health #community +1 more
Article Research

We can change the DNA of an entire species—in the wild

On Should This Exist?, Sculpting Evolution head Kevin Esvelt grapples with the potential benefits and consequences of gene drive.

via Should This Exist? · May 3, 2019
in Sculpting Evolution
#genetics #biology #engineering
Project Research

Studying the evolution of gene drive systems

How will gene drive systems evolve once released into the wild? Can they be reliably overwritten and blocked by immunizing reversal drive...

in Sculpting Evolution
Kevin Esvelt · Cody Gilleland +1 more
#bioengineering #genetics #biology
Article Research

Ed Boyden on minding your brain

A conversation between Ed Boyden and Tyler Cowen on optogenetics and expansion microscopy to storytelling and the nature of consciousness.

via Medium · April 10, 2019
in Synthetic Neurobiology
#cognition #genetics #storytelling
Project Research

Daisy Drives

Who should decide whether, when, and how to alter the environment? These are hard questions, especially when the decisions will impact pe...

in Sculpting Evolution
Kevin Esvelt · Joanna Buchthal
#bioengineering #genetics #synthetic biology +1 more
Article Research

Keeping genetic engineering localized

In a paper published in PNAS, researchers at MIT and Harvard University describe a self-limiting gene drive system.

via MIT News · April 2, 2019
in Sculpting Evolution
#bioengineering #genetics #synthetic biology
Article Research

Scientists release controversial genetically modified mosquitoes in high-security lab

Scientists hope these genetically modified "gene drive" mosquitoes could help eradicate malaria.

via NPR · Feb. 20, 2019
in Sculpting Evolution
#genetics #health #technology
Article Research

Fighting Lyme disease with gene editing

Cummings School and MIT are working with Massachusetts citizens to deploy immune mice as frontline soldiers in the war against the disease.

via Tufts Magazine · Jan. 24, 2019
in Sculpting Evolution
#genetics #health #biology
Article Research

Part 1: Gene Drive; Part 2: Gene Drive and Local Drive

iBiology features two introductory classes from CRISPR expert Kevin Esvelt, head of the Media Lab's Sculpting Evolution group.

via iBiology · July 1, 2018
in Sculpting Evolution
#genetics #biology
Article Research

Gene drive should be a nonprofit technology

Unlike a normal edit, gene drive systems could lastingly alter or suppress local or global populations of a target species.

via STAT · Nov. 27, 2018
in Sculpting Evolution
#genetics #ethics #technology
Project Research

Brainstorm: Anima Mundi

We'd like to introduce you to a very special neuroscience project that we are currently conducting in the setting of a traditional fine a...

in Sculpting Evolution
Jeantine Lunshof
#art #genetics #synthetic biology
Project Research

Search for Extra-Terrestrial Genomes (SETG)

The widespread synthesis of common organic building blocks in space could have biased life beyond Earth towards chemical similarities to ...

in Space Exploration Initiative
#genetics #space #zero gravity
Publication Research

Chimeric CRISPR guides enhance Cas9 target specificity

Noah Jakimo, Pranam Chatterjee, Joseph M. Jacobson. Chimeric CRISPR guides enhance Cas9 target specificity, doi: https://doi.org/10.1101/147686

Academic Paper, June 2017
in Molecular Machines
#genetics #synthetic biology
Archived
Project Research

Brain-Controlled Interface for the Motile Control of Spermatozoa

The reproductive organs of the female body have long been a site of contention, where opposing ideologies in religion, politics, and cult...

in Design Fiction
Anne Liu
#design #art #bioengineering +1 more
Archived
Project Research

Synthetic Genome Engineering

We are currently developing novel DNA editing technologies to broaden the scope of genome engineering. Our strategy is based on identifyi...

in Molecular Machines
Pranam Chatterjee · Noah Jakimo +1 more
#bioengineering #genetics #synthetic biology
Project Research

Responsive Science

Responsive Science is a way of conducting research that invites openness and community involvement from the earliest stages of each proje...

in Sculpting Evolution
Avery Normandin · Devora Najjar
#communications #ecology #environment +4 more
Article Research

Voters to decide on intro of altered mice to combat Lyme

Residents are invited to weigh in on a plan to release genetically-modified mice on Nantucket to combat tick-borne diseases

via Inquirer and Mirror · Aug. 3, 2017
in Sculpting Evolution
#bioengineering #genetics
Article Research

Lyme disease is spreading, and it’s partly this mouse’s fault

Black-legged ticks in forests of the Northeast and Midwest have a variety of options for the three blood meals they consume in their life...

via FiveThirtyEight · July 5, 2017
in Sculpting Evolution
#environment #genetics #health
Article Research

Transparency advocate shakes up genetic engineering

Kevin Esvelt has emerged as a leader in the debate about the ethics and politics of releasing genetically engineered animals.

via The Boston Globe · May 10, 2017
in Sculpting Evolution
#crowdsourcing #genetics #health
Article Research

This Woman Just Figured Out How to Control Sperm with Her Brain

Transdisciplinary artist Ani Liu spoke to us about her project as commentary on the state of reproductive rights today.

via Broadly · May 12, 2017
in Design Fiction
#design #genetics
Article Research

Cracking the Genetic Code with Kevin Esvelt

Kevin Esvelt leads the Sculpting Evolution Group at MIT. Their work explores “evolutionary and ecological engineering and responsive science

via The Show About Science Podcast · April 3, 2017
in Sculpting Evolution
#bioengineering #genetics
Project Research

Egstrogen Farms

A transgenic chicken commercial for ovulating womenEsgtrogen Farms is a fictional company that raises genetically modified chickens that ...

in Design Fiction
Mary Tsang
#genetics #storytelling
Project Research

Tranceflora—Amy's Glowing Silk

We collaborated with NIAS (National Institute of Agricultural Science) to genetically engineer silkworms to develop new kinds of silk for...

in Design Fiction
Sputniko!
#art #bioengineering #fashion +1 more
Article Research

How CRISPR gene editing puts scientists in the driver’s seat of evolution

Imagine you could edit a mouse’s genes to be resistant to Lyme Disease. The mouse would breed and evolution would take its course, leadin...

via PBS · Jan. 5, 2017
in Sculpting Evolution
#genetics

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