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Non-full-length G protein-coupled receptors: An unexpected discovery may lead to design new molecular devices

It was believed that functionalities of G protein-coupled receptors (GPCRs) require full-length sequences which are negated by residue de...

Article Research

Truncated immune system receptors may regulate cellular activity

Unexpected findings in chemokine receptors once believed to be non-functional open up new fields of scientific inquiry.

Research

Health 0.0

Project Research

Artificial Intelligence and Machine Learning in Clinical Development: A Translational Perspective

Technical summary: Future of clinical development is on the verge of a major transformation due to convergence of large new digital data ...

Project Research

Deep Learning to Develop and Analyze Computational Hematoxylin and Eosin Staining of Tissue Images for Digital Biopsies

Staining of tissues sections using chemical and biological dyes has been used for over a century for visualizing various tissue types and...

Project Research

Self-Learning AI Model Learns from Patient Data to Design Novel Clinical Trials

Technical summaryUnstructured learning problems without well-defined rewards are unsuitable for current reinforcement learning (RL) appro...

Project Research

Digital Clinical Trials with Novel Machine Learning and AI Architectures

Dr. Shah was an invited speaker and a contributor at The National Cancer Policy Forum developed workshop series at the The National Acade...

Research

Biomechatronics

Enhancing human physical capability

Project Research

ORBIT (Olfactory Response Baseline Identification Test)

I am currently developing a new approach in conducting sensory examinations via the Olfactory Response Baseline Identification Test (O.R....

Project Research

Research Area | Emergent Neural Networks to Redesign Clinical Testing of Medicines and Learning from Real World Evidence

Real World Data (RWD) and Real World Evidence (RWE) are playing an increasing role in healthcare decisions to support innovative use of E...

Project Research

Research Area | Rapid Fabrication and Deployment of Medical Devices and Technologies

We have significant expertise and motivation to bring problems from the clinic and society into the laboratory to develop novel bioengine...

Publication Research

Counterpoint: Artificial legs do not make artificially fast running speeds possible

R. Kram, A. M. Grabowski, C. P. McGowan, M. B. Brown, and H. M. Herr. Counterpoint: Artificial legs do not make artificially fast running speeds possible, Journal of Applied Physiology, vol. 108, no. 4, pp. 1012–1014, Apr. 2010.

Publication Research

Effects of a powered ankle-foot prosthesis on kinetic loading of the contralateral limb: a case series

D. Hill and H. M. Herr. Effects of a powered ankle-foot prosthesis on kinetic loading of the contralateral limb: a case series, Proceedings of the IEEE International Conference on Rehabilitation Robotics, 2013.

Publication Research

The fastest runner on artificial legs: Different limbs similar function?

P. G. Weyand, M. W. Bundle, C. P. McGowan, A. Grabowski, M. B. Brown, R. Kram, and H. Herr. The fastest runner on artificial legs: Different limbs, similar function?, Journal of Applied Physiology, vol. 107, no. 3, pp. 903–911, Sep. 2009.

Publication Research

Leg stiffness of sprinters using running-specific prostheses

C. P. McGowan, A. M. Grabowski, W. J. McDermott, H. M. Herr, and R. Kram. Leg stiffness of sprinters using running-specific prostheses, Journal of the Royal Society Interface, vol. 9, no. 73, pp. 1975-1982, 2012.

Publication Research

Bionic ankle-foot prosthesis normalizes walking gait for persons with leg amputation

H. M. Herr and A. M. Grabowski. Bionic ankle-foot prosthesis normalizes walking gait for persons with leg amputation, Proceedings of the Royal Society B, vol. 279, no. 1728, pp. 457–464, Feb. 2012.

Publication Research

Running-specific prostheses limit ground-force during sprinting

A. M. Grabowski, C. P. McGowan, W. J. McDermott, M. T. Beale, R. Kram, and H. M. Herr. Running-specific prostheses limit ground-force during sprinting, Biology Letters, vol. 6, no. 2, pp. 201-204, 2010.