Advancing human wellbeing by developing new ways to communicate, understand, and respond to emotion

Matton, Katie & Balaji, Purvaja & Ghasemzadeh, Hamzeh & Cooper, Jameson & Mehta, Daryush & Van Stan, Jarrad & Hillman, Robert & Picard, Rosalind & Guttag, John & Abulnaga, Mazdak. (2025). Classifying Phonotrauma Severity from Vocal Fold Images with Soft Ordinal Regression. 10.48550/arXiv.2511.09702.

Zhang, C., Kim, M., Ghorbani, S., Wu, J., Picard, R., Maes, P., & Liang, P. P. (2025). When One Modality Sabotages the Others: A Diagnostic Lens on Multimodal Reasoning. arXiv preprint arXiv:2511.02794.

Jocelyn Scheirer, Rosalind Picard, and Aubrey Cantrell. 2025. Personalized Animations for Affective Feedback: Generative AI Helps to Visualize Skin Conductance. In Proceedings of the 3rd International Workshop on Multimodal and Responsible Affective Computing (MRAC '25). Association for Computing Machinery, New York, NY, USA, 146–151. https://doi.org/10.1145/3746270.3760237

*Senthil, S., *Fedor, S., Zhang, B., Nathan, V., Stickgold, R., Picard, R. W., Associations Between Circadian Sleep Alignment, Sleep Regularity, and Wellbeing: Evidence from Wearable Data, In *Proceedings of the IEEE-EMBS International Conference on Biomedical and Health Informatics (BHI’25), Atlanta, GA, USA

Kim, M., Wang, W., Long, J., Picard, R., Barczi, N., & Maes, P. (2025). Reflective Agency: Ethical and Empirical Framework for AI-Mediated Self-Reflection Systems. Proceedings of the AAAI/ACM Conference on AI, Ethics, and Society, 8(2), 1440-1452. https://doi.org/10.1609/aies.v8i2.36644

Wazeer Zulfikar, Treyden Chiaravalloti, Jocelyn Shen, Rosalind Picard, and Pattie Maes. 2025. Resonance: Drawing from Memories to Imagine Positive Futures through AI-Augmented Journaling. In Proceedings of the Augmented Humans International Conference 2025 (AHs '25). Association for Computing Machinery, New York, NY, USA, 199–215. https://doi.org/10.1145/3745900.3746099

Lewis, R., Fedor, S., Julia, N.H., Curtiss, J., Kim, J., Jones, N., Mischoulon, D., Quatieri, T.F., Cummins, N., Pedrelli, P., & Picard, R.W. (2025). Towards the Objective Characterisation of Major Depressive Disorder Using Speech Data from a 12-week Observational Study with Daily Measurements. Interspeech 2025.

Hidalgo Julia, N.*, Lewis, R., Ferguson*, C., Goldberg, S., Lau, W., Swords, C., Valdivia, G., Wilson-Mendenhall, C., Tartar, R., Picard, R., Davidson, R. (2025) Identifying Vocal and Facial Biomarkers of Depression in Large-Scale Remote Recordings: A Multimodal Study Using Mixed-Effects Modeling. Proc. Interspeech 2025, 5263-5267, doi: 10.21437/Interspeech.2025-2560

Zhang, B., Fedor, S., Stickgold, R., Freedman, M., Nathan, V., Viswanath, V. K., Rahman, S., Duffy, J. F., Czeisler, C. A., & Picard, R. W. (2025, June). Estimating central circadian phase with wrist-worn spectrophotometer in ambulatory environment. Presented at SLEEP 2025: 38th Annual Meeting of the Associated Professional Sleep Societies, Seattle, WA, United States.

Chylek, D., Fedor, S., Zhang, B., Nathan, V., Freedman, M., Stickgold, R., & Picard, R. (2025, June). Evidence for a deep sleep homeostatic response in ambulatory settings. SLEEP 2025: 38th Annual Meeting of the Associated Professional Sleep Societies, Seattle, WA, United States.

Christine Wu, Ila Krishna Kumar, and Rosalind Picard. 2025. Navigating Emotions Through Art: Recommendations for Designing Art-Therapy Based Chatbots for Trauma-Impacted Youth: Recommendations for Designing Art-Therapy Based Chatbots for Trauma-Impacted Youth. In Proceedings of the Extended Abstracts of the CHI Conference on Human Factors in Computing Systems (CHI EA '25).

Wazeer Zulfikar, Treyden Chiaravalloti, Jocelyn Shen, Rosalind Picard, and Pattie Maes. 2025. Resonance: Drawing from Memories to Imagine Positive Futures through AI-Augmented Journaling. In The Augmented Humans International Conference 2025 (AHs 2025), March 16–20, 2025, Masdar City, Abu Dhabi, United Arab Emirates. ACM, New York, NY, USA, 17 pages.

Bustos, Cristina & Sole-Ribalta, Albert & Elhaouij, Neska & Borge-Holthoefer, Javier & Lapedriza, Àgata & Picard, Rosalind. (2025). Analyzing the Visual Road Scene for Driver Stress Estimation. IEEE Transactions on Affective Computing. PP. 1-16. 10.1109/TAFFC.2025.3539003.

Bustos, C., Sole-Ribalta, A., Elhaouij, N., Borge-Holthoefer, J., Lapedriza, A., & Picard, R. (2025). Analyzing the visual road scene for driver stress estimation. IEEE Transactions on Affective Computing, 16(3), 1787–1801. https://doi.org/10.1109/TAFFC.2025.3539003

Hamlett GE, Schrader C, Ferguson C, Kobylski LA, Picard R, Locascio JJ, McNally RJ, Cohen LS, Vanderkruik R. Considering Comorbidities and Individual Differences in Testing a Gaming Behavioral Activation App for Perinatal Depression and Anxiety: Open Trial Pilot Intervention Study. JMIR Form Res. 2025 Jan 14;9:e59154. doi: 10.2196/59154. PMID: 39810410; PMCID: PMC11750158.

Groh, M., Sankaranarayanan, A., Singh, N. et al. Human detection of political speech deepfakes across transcripts, audio, and video. Nat Commun 15, 7629 (2024). https://doi.org/10.1038/s41467-024-51998-z

Choi, S., Fedor, S., Stickgold, R., Sano, A., Nathan, V., Freedman, M., & Picard, R. (2024). Sleep regularity and duration are associated with daily self-reported wellbeing. In Proceedings of the 46th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE.

Choi, S., Fedor, S., Stickgold, R., Nathan, V., Freedman, M., & Picard, R. (2024). Predicting self-reported wellbeing from sleep with mixed effects random forest. In Proceedings of the 46th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE.

Geoffrey S. Ginsburg, Rosalind W. Picard, and Stephen H. Friend. "Key Issues as Wearable Digital Health Technologies Enter Clinical Care." New England Journal of Medicine 2024; 390:1118-27. DOI: 10.1056/NEJMra2307160

Elizabeth Donner, Orrin Devinsky, and Daniel Friedman; guest editors Stephen H. Friend, Geoffrey S. Ginsburg, Rosalind W. Picard, Jeffrey M. Drazen. "Wearable Digital Health Technology for Epilepsy." New England Journal of Medicine 2024; 390:736-745. DOI: 10.1056/NEJMra2301913

Groh, M., Badri, O., Daneshjou, R. et al. Deep learning-aided decision support for diagnosis of skin disease across skin tones. Nat Med (2024). https://doi.org/10.1038/s41591-023-02728-3

Vanderkruik RC, Ferguson C, Kobylski LA, Locascio JJ, Hamlett GE, Killenberg PC, Lewis R, Jones N, Rossa ET, Dineen H, Picard R, Cohen LS Testing a Behavioral Activation Gaming App for Depression During Pregnancy: Multimethod Pilot Study JMIR Form Res 2024;8:e44029

Erica S. Spatz, Geoffrey S. Ginsburg, John S. Rumsfeld, and Mintu P. Turakhia; guest editors Stephen H. Friend, Geoffrey S. Ginsburg, Rosalind W. Picard, Jeffrey M. Drazen. "Wearable Digital Health Technologies for Monitoring in Cardiovascular Medicine." New England Journal of Medicine 2024; 390:346-356. DOI: 10.1056/NEJMra2301903

Fedor, S., Lewis, R., Pedrelli, P., Mischoulon, D., Curtiss, J., & Picard, R. W. (2023). Wearable technology in clinical practice for depressive disorder. New England Journal of Medicine, 389(26), 2457-2466.

*Lewis, R. A., *Matton, K., Picard, R., & Guttag, J. (2023, December). Improving Domain Generalization in Contrastive Learning using Domain-Aware Temperature Control. In NeurIPS 2023 Workshop on Distribution Shifts: New Frontiers with Foundation Models & Neurips 2023 Workshop on Self-supervised Learning (*Equal contribution)

B. Zhang, W. V. Chen, G. Regalia, D. M. Goldenholz, and R. W. Picard, “Sleep deficiency is associated with higher next-day generalized tonic-clonic seizure risk”, in American Epilepsy Society 2023 Annual Meeting, 2023.

Friend, Stephen H., Geoffrey S. Ginsburg, and Rosalind W. Picard. "Wearable Digital Health Technology." New England Journal of Medicine 389.22 (2023): 2100-2101.

Michael S. Hughes, Ananta Addala, and Bruce Buckingham; guest editors Stephen H. Friend, Geoffrey S. Ginsburg, Rosalind W. Picard, Jeffrey M. Drazen. "Digital Technology for Diabetes." New England Journal of Medicine 2023; 389:2076-2086. DOI: 10.1056/NEJMra2215899

Kumar, I. K. (2023). FOSTERING WELL-BEING: Designing Technology to Improve the Psychological Well-being of Foster-Involved Youth (thesis).

Epstein, Hertzmann, et al. "Art and the science of generative AI." Science 380.6650 (2023): 1110-1111.

Kubzansky LD, Kim ES, Boehm JK, Davidson RJ, Huffman JC, Loucks EB, Lyubomirsky S, Picard RW, Schueller SM, Trudel-Fitzgerald C, VanderWeele TJ, Warran K, Yeager DS, Yeh CS, Moskowitz JT. Interventions to Modify Psychological Well-Being: Progress, Promises, and an Agenda for Future Research. Affect Sci. 2023 Mar 3;4(1):174-184. doi: 10.1007/s42761-022-00167-w. PMID: 37064816; PMCID: PMC9982781.

Coppersmith DDL, Wang SB, Kleiman EM, Maimone JS, Fedor S, Bentley KH, Millner AJ, Fortgang RG, Picard RW, Beck S, Huffman JC, Nock MK. Real-time Digital Monitoring of a Suicide Attempt by a Hospital Patient. General Hospital Psychiatry. 2023;80:35-39. doi: 10.1016/j.genhosppsych.2022.12.005

Contrastive Learning of Electrodermal Activity Representations for Stress Detection; Matton, K*, Lewis, R*, Guttag, J, Picard, R.W. Conference on Health, Inference, and Learning (CHIL) 2023. *Equal contribution

Groh, Matthew, Caleb Harris, Roxana Daneshjou, Omar Badri, and Arash Koochek. "Towards transparency in dermatology image datasets with skin tone annotations by experts, crowds, and an algorithm." CSCW (2022).

Groh, Matthew. "Identifying the Context Shift between Test Benchmarks and Production Data." arXiv preprint arXiv:2207.01059 (2022).

Groh, Matthew, Craig Ferguson, Robert Lewis, and Rosalind W. Picard. "Computational Empathy Counteracts the Negative Effects of Anger on Creative Problem Solving." In 2022 10th International Conference on Affective Computing and Intelligent Interaction (ACII), pp. 1-8. IEEE, 2022.

Richter-Lunn, K., & Krishna Kumar, I. (2022). Acu.ation: Real Time Acupoint Stimulation To Mediate The Urge To Smoke. Extended Abstracts of the 2022 CHI Conference on Human Factors in Computing Systems, 1–7. https://doi.org/10.1145/3491101.3519636

Can a Recommender System Support Treatment Personalisation in Digital Mental Health Therapy? A Quantitative Feasibility Assessment Using Data from a Behavioural Activation Therapy App, Lewis, R., Ferguson, F., Wilks, C., Jones, N., Picard, R.W.; CHI Conference on Human Factors in Computing Systems Extended Abstracts (CHI ’22 Extended Abstracts)

Matthew Groh, Ziv Epstein, Chaz Firestone, Rosalind Picard. "Deepfake detection by human crowds, machines, and machine-informed crowds." Proceedings of the National Academy of Sciences Jan 2022, 119 (1) e2110013119; DOI: 10.1073/pnas.2110013119

Schuller, Björn & Picard, Rosalind & Andre, Elisabeth & Gratch, Jonathan & Tao, Jianhua. (2021). Intelligent Signal Processing for Affective Computing [From the Guest Editors]. IEEE Signal Processing Magazine. 38. 9-11. 10.1109/MSP.2021.3096415.

Chiang S, Picard RW, Chiong W, Moss R, Worrell GA, Rao VR, Goldenholz DM. Guidelines for Conducting Ethical Artificial Intelligence Research in Neurology: A Systematic Approach for Clinicians and Researchers. Neurology. 2021 Sep 28;97(13):632-640. doi: 10.1212/WNL.0000000000012570. Epub 2021 Jul 27. PMID: 34315785; PMCID: PMC8480407.

Cristina Bustos, Neska Elhaouij, Albert Sole-Ribalta, Javier Borge-Holthoefer, Agata Lapedriza, and Rosalind Picard. "Predicting Driver Self-Reported Stress by Analyzing the Road Scene." in Proceedings of International Conference on Affective Computing and Intelligent Interaction (ACII 2021), preprint arXiv:2109.13225 (2021).

Sankaranarayanan, Aruna, Matthew Groh, Rosalind Picard, and Andrew Lippman. "The Presidential Deepfakes Dataset." (2021).

Onorati F, Regalia G, Caborni C, LaFrance WC Jr, Blum AS, Bidwell J, De Liso P, El Atrache R, Loddenkemper T, Mohammadpour-Touserkani F, Sarkis RA, Friedman D, Jeschke J, Picard R. Prospective Study of a Multimodal Convulsive Seizure Detection Wearable System on Pediatric and Adult Patients in the Epilepsy Monitoring Unit. Front Neurol. 2021 Aug 18;12:724904. doi: 10.3389/fneur.2021.724904. PMID:

Ferguson, C.* and Lewis, R.*, Wilks, C., Picard, R.W.; The Guardians: Designing a Game for Long-term Engagement with Mental Health Therapy; IEEE Conference of Games 2021. *Equal contribution

Robert Lewis, Yuanbo Liu, Matthew Groh and Rosalind Picard, "Habit Formation Dynamics: Finding Factors Associated with Building Strong Mindfulness Habits" HCI International 2021

R. Lewis, A. Ghandeharioun, S. Fedor, P. Pedrelli, R.W. Picard, D. Mischoulon, "Mixed Effects Random Forests for Personalised Predictions of Clinical Depression Severity", ICML 2021 Computational Approaches to Mental Health workshop

Rosalind W. Picard, Edward W. Boyer, Smartwatch biomarkers and the path to clinical use, Med, Volume 2, Issue 7, 2021, Pages 797-799, ISSN 2666-6340, https://doi.org/10.1016/j.medj.2021.06.005.

Nock, M. K., Kleiman, E. M., Abraham, M., Bentley, K. H., Brent, D. A., Buonopane, R. J., … Pearson, J. L. (2021). Consensus Statement on Ethical & Safety Practices for Conducting Digital Monitoring Studies with People at Risk of Suicide and Related Behaviors. Psychiatric Research and Clinical Practice, 3(2), 57–66. https://doi.org/10.1176/appi.prcp.20200029

Jinmo Lee, Neska Elhaouij, and Rosalind Picard. 2021. AmbientBreath: Unobtrusive Just-in-time Breathing Intervention Using Multi-sensory Stimulation and its Evaluation in a Car Simulator. Proc. ACM Interact. Mob. Wearable Ubiquitous Technol. 5, 2, Article 71 (June 2021), 30 pages. DOI:https://doi.org/10.1145/3463493

Groh, Matthew, Caleb Harris, Luis Soenksen, Felix Lau, Rachel Han, Aerin Kim, Arash Koochek, and Omar Badri. "Evaluating Deep Neural Networks Trained on Clinical Images in Dermatology with the Fitzpatrick 17k Dataset." arXiv preprint arXiv:2104.09957 (2021). Accepted at CVPR ISIC 2021 workshop. Publication pending.

Kyung Yun Choi, Jinmo Lee, Neska El Haouij, Rosalind W. Picard, and Hiroshi Ishii. 2021. aSpire: Clippable, Mobile Pneumatic-Haptic Device for Breathing Rate Regulation via Personalizable Tactile Feedback. In CHI Conference on Human Factors in Computing Systems Extended Abstracts (CHI ’21 Extended Abstracts), May 8–13, 2021, Yokohama, Japan. ACM, New York, NY, USA, 7 pages.

Lewis, Robert, et al. "Shaping Habit Formation Insights with Shapley Values: Towards an Explainable AI-system for Self-understanding and Health Behavior Change." CHI 2021 Workshop Paper. Realizing AI in Healthcare: Challenges Appearing in the Wild.

McHill AW, Sano A, Hilditch CJ, Barger LK, Czeisler CA, Picard R, Klerman EB. Robust stability of melatonin circadian phase, sleep metrics, and chronotype across months in young adults living in real-world settings. J Pineal Res. 2021 Apr;70(3):e12720. doi: 10.1111/jpi.12720. Epub 2021 Feb 16. PMID: 33523499; PMCID: PMC9135480.

Regalia G, Gerboni G, Migliorini M, Lai M, Pham J, Puri N, Pavlova MK, Picard RW, Sarkis RA, Onorati F. Sleep assessment by means of a wrist actigraphy-based algorithm: agreement with polysomnography in an ambulatory study on older adults. Chronobiol Int. 2021 Mar;38(3):400-414. doi: 10.1080/07420528.2020.1835942. Epub 2020 Nov 19. Erratum in: Chronobiol Int. 2022 Jul;39(7):I. doi: 10.1080/0742052

Pedrelli, P., Fedor, S., Ghandeharioun, A., Howe, E., Ionescu, D. F., Bhathena, D., ... & Picard, R. W. (2020). Monitoring changes in depression severity using wearable and mobile sensors. Frontiers in psychiatry, 11, 1413.

Hedman E, Schoen SA, Miller LJ, Picard R. Wireless Measurement of Sympathetic Arousal During in vivo Occupational Therapy Sessions. Front Integr Neurosci. 2020 Oct 29;14:539875. doi: 10.3389/fnint.2020.539875. PMID: 33192351; PMCID: PMC7659428.