Hugh Herr

Professor of Media Arts and Sciences
Publication

Mechanoneural interfaces for bionic integration

Shu, T., Herrera-Arcos, G., Taylor, C.R. et al. Mechanoneural interfaces for bionic integration. Nat Rev Bioeng (2024). https://doi.org/10.1038/s44222-024-00151-y

Publication

Resting State Neurophysiology of Agonist-Antagonist Myoneural Interface in Persons with Transtibial Amputation

L. Chicos, D. Rangaprakash, R. Barry, H. Herr, Resting State Neurophysiology of Agonist-Antagonist Myoneural Interface in Persons with Transtibial Amputation. under review at Nature Communications Medicine. (2023).

Publication

Agonist-antagonist Muscle Strain in the Residual Limb Preserves Motor Control and Perception after Amputation

Song H, Israel EA, Gutierrez-Arango S, Teng AC, Srinivasan SS, Freed LE, Herr HM. Agonist-antagonist Muscle Strain in the Residual Limb Preserves Motor Control and Perception after Amputation. Communication Medicine (Lond). 2022 Aug 5;2:97. doi: 0.1038/s43856-022-00162-z PMID35942078; PMC9356003 2022 (Publisher Correction 2022 Sep 26;2:121. doi: 10.1038/s43856-022-00188-3).

Publication

The Agonist-antagonist Myoneural Interface

Herr HM, Carty MJ. The Agonist-antagonist Myoneural Interface. Tech Orthop. 2021 Dec;36(4):337-344. doi: 10.1097/bto.0000000000000552. PMID: 34866774; PMCID: PMC8630671.

Publication

Magnetomicrometry

C. R. Taylor, S. S. Srinivasan, S. H. Yeon, M. K. O'Donnell, T. J. Roberts, H. M. Herr, Magnetomicrometry, Sci.Robot. 6, eabg0656 (2021), DOI: 10.1126/scirobotics.abg0656

Publication

The Agonist-Antagonist Myoneural Interface

Carty, M.J. and Herr, H.M. The Agonist-Antagonist Myoneural Interface. Hand Clinics. 2021 Aug;37(3):435-445. doi: 10.1016/j.hcl.2021.04.006. https://pubmed.ncbi.nlm.nih.gov/34253316/

Publication

Acquisition of Surface EMG Using Flexible and Low-Profile Electrodes for Lower Extremity Neuroprosthetic Control

Yeon SH, Shu T, Song H, Hsieh TH, Qiao J, Rogers EA, Gutierrez-Arango S, Israel E, Freed LE, Herr HM. Acquisition of Surface EMG Using Flexible and Low-Profile Electrodes for Lower Extremity Neuroprosthetic Control. IEEE Trans Med Robot Bionics. 2021 Aug;3(3):563-572. doi: 10.1109/TMRB.2021.3098952. PMID: 34738079; PMCID: PMC8562690.

Publication

Design and preliminary results of a reaction force series elastic actuator for bionic knee and ankle prostheses

M. E. Carney, T. Shu, R. Stolyarov, J. F. Duval and H. M. Herr, "Design and Preliminary Results of a Reaction Force Series Elastic Actuator for Bionic Knee and Ankle Prostheses," in IEEE Transactions on Medical Robotics and Bionics, vol. 3, no. 3, pp. 542-553, Aug. 2021, doi: 10.1109/TMRB.2021.3098921.

Publication

Neural Interfacing Architecture Enables Enhanced Motor Control and Residual Limb Functionality Post Amputation

Srinivasan SS, Gutierrez-Arango S, Teng AC, Israel E, Song H, Bailey ZK, Carty MJ, Freed LE, Herr HM. Neural interfacing architecture enables enhanced motor control and residual limb functionality postamputation. Proc Natl Acad Sci U S A. 2021 Mar 2;118(9):e2019555118. doi: 10.1073/pnas.2019555118

Publication

A cutaneous mechanoneural interface for neuroprosthetic feedback

S. Srinivasan, S., M. Herr, H. A cutaneous mechanoneural interface for neuroprosthetic feedback. Nat Biomed Eng (2021). https://doi.org/10.1038/s41551-020-00669-7

Publication

Flexible Dry Electrodes for EMG Acquisition within Lower Extremity Prosthetic Sockets

Yeon, Seong Ho, et al. "Flexible Dry Electrodes for EMG Acquisition within Lower Extremity Prosthetic Sockets." 2020 8th IEEE RAS/EMBS International Conference for Biomedical Robotics and Biomechatronics (BioRob). IEEE.

Publication

An Ankle-Foot Prosthesis for Rock Climbing Augmentation

E. A. Rogers, M. E. Carney, S. H. Yeon, T. R. Clites, D. Solav and H. M. Herr, "An Ankle-Foot Prosthesis for Rock Climbing Augmentation," in IEEE Transactions on Neural Systems and Rehabilitation Engineering, doi: 10.1109/TNSRE.2020.3033474.

Publication

Electric-Energetic Consequences of Springs in Lower-Extremity Powered Prostheses on Varied Terrain

M. E. Carney and H. Herr, "Electric-Energetic Consequences of Springs in Lower-Extremity Powered Prostheses on Varied Terrain," 2020 8th IEEE RAS/EMBS International Conference for Biomedical Robotics and Biomechatronics (BioRob), New York City, NY, USA, 2020, pp. 989-996, doi: 10.1109/BioRob49111.2020.9224458.

Publication

Magnetomicrometry: Tissue Length Tracking via Implanted Magnetic Beads

C. Taylor, Magnetomicrometry : Tissue length tracking via implanted magnetic beads (2020). https://dspace.mit.edu/handle/1721.1/130210

Publication

Low-latency tracking of multiple permanent magnets

C. R. Taylor, H. G. Abramson, and H. M. Herr, “Low-Latency Tracking of Multiple Permanent Magnets,” IEEE Sensors Journal, pp. 1–11, 2019.

Publication

Coordination of Lower Limb Movement Utilizing the Agonist-Antagonist Myoneural Interface

Publication

Retinal supplementation augments optogenetic stimulation efficacy in vivo

S. Srinivasan, B. Schelhaas, B. E. Maimon, H. Song, H. M. Herr, Retinal supplementation augments optogenetic stimulation efficacy in vivo. J. Neural Eng. (2019)

Publication

A caprine model of the agonist-antagonist myoneural interface as implemented at the above- and below-knee amputation levels.

T. R. Clites, M. J. Carty, S. S. Srinivasan, S. G. Talbot, R. Branemark, H. M. Herr, A caprine model of the agonist-antagonist myoneural interface as implemented at the above- and below-knee amputation levels.: Plastic and Reconstructive Surgery. 2019

Publication

Polyimide Electrode-Based Electrical Stimulation Impedes Early Stage Muscle Graft Regeneration

S. Srinivasan, K. Vyas, M. McAvoy, P. Calvaresi, O. Khan, R. Langer, D. Anderson, H. Herr, Polyimide Electrode-based Electrical Stimulation Impedes Early Stage Muscle Graft Regeneration. Front. Neurol. 10 (2019),

Publication

Towards functional restoration for persons with limb amputation: A dual-stage implementation of regenerative AMIs

S. S. Srinivasan, M. Diaz, M. Carty, H. M. Herr, Towards functional restoration for persons with limb amputation: A dual-stage implementation of regenerative agonist-antagonist myoneural interfaces. Sci. Rep. 9, 1981 (2019).

Publication

A Framework for Measuring the Time-Varying Shape and Full-Field Deformation of Residual Limbs Using 3-D Digital Image Correlation

Solav, D., Moerman, K. M., Jaeger, A. M., & Herr, H. (2019). A framework for measuring the time-varying shape and full-field deformation of residual limbs using 3D digital image correlation. IEEE Transactions on Biomedical Engineering, 66(10), 2740-2752.

Publication

Closed-loop functional optogenetic stimulation

Shriya S. Srinivasan, Benjamin E. Maimon, Maurizio Diaz, Hyungeun Song and Hugh M. Herr, Nature Communications, volume 9, article number: 5303 (2018)

Publication

MultiDIC: An Open-Source Toolbox for Multi-View 3D Digital Image Correlation

Solav, D., K. M. Moerman, A. M. Jaeger, K. Genovese, and H. M. Herr. MultiDIC: an Open-Source Toolbox for Multi-View 3D Digital Image Correlation. IEEE Access 6:30520–30535, 2018.

Publication

Proprioception from a neurally controlled lower-extremity prosthesis

T. R. Clites, M. J. Carty, J. B. Ullauri, M. E. Carney, L. M. Mooney, J.-F. Duval, S. S. Srinivasan, H. M. Herr, Proprioception from a neurally controlled lower-extremity prosthesis. Sci. Transl. Med. 10, eaap8373 (2018).

Publication

Development and Evaluation of a Powered Artificial Gastrocnemius for Transtibial Amputee Gait

M. Eilenberg, J. Kuan, and H. Herr. Development and Evaluation of a Powered Artificial Gastrocnemius for Transtibial Amputee Gait, Journal of Robotics, vol. 2018, Article ID 5951965, 15 pages, 2018.

Publication

Translational Motion Tracking of Leg Joints for Enhanced Prediction of Walking Tasks

Stolyarov, R. M., Burnett, G., & Herr, H. (2017). Translational Motion Tracking of Leg Joints for Enhanced Prediction of Walking Tasks. IEEE Transactions on Biomedical Engineering, 1-1. doi:10.1109/tbme.2017.2718528

Publication

On prosthetic control: A regenerative agonist-antagonist myoneural interface

S. S. Srinivasan, M. J. Carty, P. W. Calvaresi, T. R. Clites, B. E. Maimon, C. R. Taylor, A. N. Zorzos, H. Herr, On prosthetic control : A regenerative agonist-antagonist myoneural interface, 2, eaan2971 (2017).

Publication

A Caprine Model of a Novel Amputation Paradigm for Bi-directional Neural Control of a Bionic Limb

T. R. Clites, M. J. Carty, H. M. Herr, in Plastic Surgery Research Council, (2017), p. 119.

Publication

A murine model of a novel surgical architecture for proprioceptive muscle feedback

T. R. Clites, M. J. Carty, S. Srinivasan, A. N. Zorzos, H. M. Herr, A murine model of a novel surgical architecture for proprioceptive muscle feedback and its potential application to control of advanced limb prostheses., J. Neural Eng. 14, aa614b (2017).

Publication

Transdermal optogenetic peripheral nerve stimulation

Maimon BE, Zorzos AN, Bendell R, Harding A, Fahmi M, Srinivasan S, Calvaresi P, Herr HM. J Neural Eng. 2017 Feb 3;14(3): 034002

Publication

Low-Cost Methodology for Skin Strain Measurement of a Flexed Biological Limb.

Lin, B., Moerman, K. M., McMahan, C. G., Pasch, K. A., & Herr, H. M. Low-Cost Methodology for Skin Strain Measurement of a Flexed Biological Limb. IEEE Transactions on Biomedical Engineering, PP(99), 2016.

Publication

FlexSEA: Flexible Scalable Electronics Architecture for Wearable Robotic Applications

J.F. Duval, H. M. Herr

Publication

FlexSEA-Execute: Advanced Motion Controller for Wearable Robotic Applications

J.F. Duval, H. M. Herr

Publication

Human Leg Model Predicts Muscle Forces, States, and Energetics during Walking

J. Markowitz and H. Herr. Human Leg Model Predicts Muscle Forces, States, and Energetics during Walking, PLoS Computational Biology, vol. 5, no. 12, May. 2016.

Publication

Assessment of Nerve Regeneration through a Novel Microchannel Array

B. Maimon, A. N. Zorzos, K. W. Song, R. Bendell, R. Riso, H. M. Herr

Publication

Multi-Material 3-D Viscoelastic Model of a Transtibial Residuum from In-vivo Indentation and MRI Data

Sengeh DM, Moerman, K. M., Petron A, Herr H.M.

Publication

Method And System For Providing Proprioceptive Feedback And Functionality Mitigating Limb Pathology

H. M. Herr, T. R. Clites, B. Maimon, A. Zorzos, M. J. Carty, J.-F. Duval, Method And System For Providing Proprioceptive Feedback And Functionality Mitigating Limb Pathology. US Pending Patent 62/276422 (2016).

Publication

Biomechanical walking mechanisms underlying the metabolic reduction caused by an autonomous exoskeleton

L. M. Mooney, H. M. Herr

Publication

Peripheral Neural Interface Via Nerve Regeneration to Distal Tissues

H. M. Herr, R. R. Riso, K. W. Song, R. J.Casler, M. J. Carty, Peripheral Neural Interface Via Nerve Regeneration to Distal Tissues. US Patent US20160346099 (2016).

Publication

“Motion compensation in a tomographic ultrasound imaging system: toward volumetric scans of a limb for prosthetic socket design”

B.J. Ranger, M. Feigin, N. Pestrov, X. Zhang, V. Lempitsky, H.M. Herr, B.W. Anthony. “Motion compensation in a tomographic ultrasound imaging system: toward volumetric scans of a limb for prosthetic socket design”. Proceedings of the IEEE Engineering in Medicine and Biology Conference, 2015.

Publication

Design and testing of a bionic dance prosthesis

E. J. Rouse, N. C. Villagaray-Carski, R. W. Emerson, H. M. Herr

Publication

FlexSEA: flexible, scalable electronics architecture for wearable robotic applications

Duval, JF "FlexSEA: flexible, scalable electronics architecture for wearable robotic applications"

Publication

Autonomous exoskeleton reduces metabolic cost of human walking

L. M. Mooney, E. J. Rouse and H. M. Herr. Autonomous exoskeleton reduces metabolic cost of human walking, Journal of NeuroEngineering and Rehabilitation, vol. 11, pp. 151, November. 2014

Publication

Autonomous exoskeleton reduces metabolic cost of human walking during load carriage

L. M. Mooney, E. J. Rouse, H. M. Herr

Publication

Clutchable series-elastic actuator: Implications for prosthetic knee design

E. J. Rouse, L. M. Mooney and H. M. Herr Clutchable series-elastic actuator: Implications for prosthetic knee design International Journal of Robotics Research, 2014, in press

Publication

Design of a Clutch–Spring Knee Exoskeleton for Running

G. Elliott, A. Marecki and H. Herr. Design of a Clutch–Spring Knee Exoskeleton for Running, Journal of Medical Devices, vol 8, no. 3, 031002-031002-11, July. 2014.

Publication

Voxel-based Fabrication through Material Property Mapping

E.L. Doubrovski, Elizabeth Tsai, D. Dikovsky, J.M.P. Geraedts, Hugh Herr, Neri Oxman

Publication

Autonomous exoskeleton reduces metabolic cost of walking

L. M. Mooney, E. J. Rouse and H. M. Herr. Autonomous exoskeleton reduces metabolic cost of walking, International Conference of the IEEE Engineering in Medicine and Biology Society, August. 2014.

Publication

A variable impedance prosthetic socket for a transtibial amputee designed from MRI data

D. Sengeh, H. M. Herr

Publication

A clutchable series-elastic actuator: design of a robotic knee prosthesis for minimum energy consumption

E. J. Rouse, L. M. Mooney, E. C. Martinez-Villalpando and H. M. Herr A clutchable series-elastic actuator: design of a robotic knee prosthesis for minimum energy consumption, Proceedings of the IEEE International Conference on Rehabilitation Robotics, 2013

Publication

Continuously-Variable Series-Elastic Actuator

L. M. Mooney and H. M. Herr Continuously-Variable Series-Elastic Actuator, Proceedings of the IEEE International Conference on Rehabilitation Robotics, 2013

Publication

Proportional EMG Control of Ankle Plantar Flexion in a Powered Transtibial Prosthesis

J. Wang, O. A. Kannape, and H. M. Herr Proportional EMG Control of Ankle Plantar Flexion in a Powered Transtibial Prosthesis, Proceedings of the IEEE International Conference on Rehabilitation Robotics, 2013

Publication

Effects of a powered ankle-foot prosthesis on kinetic loading of the contralateral limb: a case series

D. Hill and H. M. Herr. Effects of a powered ankle-foot prosthesis on kinetic loading of the contralateral limb: a case series, Proceedings of the IEEE International Conference on Rehabilitation Robotics, 2013.

Publication

Pattern Classification of Terrain During Amputee Walking

Farrell, M. T. "Pattern Classification of Terrain During Amputee Walking"

Publication

The biomechanics and energetics of human running using an elastic knee exoskeleton

G. Elliott, G.S. Sawicki, A. Marecki, H. Herr. The biomechanics and energetics of human running using an elastic knee exoskeleton, International Conference on Rehabilitation Robotics, 2013.

Publication

Effects of a Powered Ankle Prosthesis on Shock Absorption and Residual Limb/Socket Interface Pressure

Hill, D. "Effects of a Powered Ankle Prosthesis on Shock Absorption and Residual Limb/Socket Interface Pressure"

Publication

Advanced Prototyping of Variable Impedance Prosthetic Sockets for Trans-tibial Amputees: Polyjet Matrix 3D Printing of Comfortable Prostheti

Sengeh, D. "Advanced Prototyping of Variable Impedance Prosthetic Sockets for Trans-tibial Amputees: Polyjet Matrix 3D Printing of Comfortable Prosthetic Sockets Using Digital Anatomical Data"

Publication

Design and Evaluation of a Biomimetic Agonist-Antagonist Active Knee Prosthesis

Martinez-Villalpando, E. "Design and Evaluation of a Biomimetic Agonist-Antagonist Active Knee Prosthesis"

Publication

Leg stiffness of sprinters using running-specific prostheses

C. P. McGowan, A. M. Grabowski, W. J. McDermott, H. M. Herr, and R. Kram. Leg stiffness of sprinters using running-specific prostheses, Journal of the Royal Society Interface, vol. 9, no. 73, pp. 1975-1982, 2012.

Publication

A method to determine the optimal features for control of a powered lower-limb prostheses

M. T. Farrell, H. M. Herr

Publication

Antagonistic Active Knee Prosthesis. A Metabolic Cost of Walking Comparison with a Variable-Damping Prosthetic Knee

E. C. Martinez-Villalpando, L. M. Mooney, G. A. Elliott and H. M. Herr. Antagonistic Active Knee Prosthesis. A Metabolic Cost of Walking Comparison with a Variable-Damping Prosthetic Knee, Engineering in Medicine and Biology Society, EMBC, 2011 Annual International Conference of the IEEE, 2011.

Publication

Bionic ankle-foot prosthesis normalizes walking gait for persons with leg amputation

H. M. Herr and A. M. Grabowski. Bionic ankle-foot prosthesis normalizes walking gait for persons with leg amputation, Proceedings of the Royal Society B, vol. 279, no. 1728, pp. 457–464, Feb. 2012.

Publication

Human leg model predicts ankle muscle-tendon morphology state roles and energetics in walking

P. Krishnaswamy, E. N. Brown, H. M. Herr

Publication

Speed adaptation in a powered transtibial prosthesis controlled with a neuromuscular model

J. Markowitz, P. Krishnaswamy, M. F. Eilenberg, K. Endo, C. Barnhart, H. M. Herr

Publication

A muscle-reflex model that encodes principles of legged mechanics produces human walking dynamics and muscle activities

H. Geyer and H. Herr. A muscle-reflex model that encodes principles of legged mechanics produces human walking dynamics and muscle activities, IEEE Transactions on Neural Systems & Rehabilitation Engineering, 2010.

Publication

Optimal workloop energetics of muscle-actuated systems an impedance matching view

W. Farahat and H. M. Herr. Optimal workloop energetics of muscle-actuated systems an impedance matching view, PLoS Computational Biology, vol. 6, no. 6, 2010.

Publication

Control of a powered ankle-foot prosthesis based on a neuromuscular model

M. F. Eilenberg, H. Geyer, and H. M. Herr. Control of a powered ankle-foot prosthesis based on a neuromuscular model, IEEE Transactions on Neural Systems and Rehabilitation Engineering, vol. 18, no. 2, pp. 164-173, 2010.

Publication

Counterpoint: Artificial legs do not make artificially fast running speeds possible

R. Kram, A. M. Grabowski, C. P. McGowan, M. B. Brown, and H. M. Herr. Counterpoint: Artificial legs do not make artificially fast running speeds possible, Journal of Applied Physiology, vol. 108, no. 4, pp. 1012–1014, Apr. 2010.

Publication

Running-specific prostheses limit ground-force during sprinting

A. M. Grabowski, C. P. McGowan, W. J. McDermott, M. T. Beale, R. Kram, and H. M. Herr. Running-specific prostheses limit ground-force during sprinting, Biology Letters, vol. 6, no. 2, pp. 201-204, 2010.

Publication

Human walking model predicts joint mechanics electromyography and mechanical economy

K. Endo and H. Herr. Human walking model predicts joint mechanics, electromyography and mechanical economy, IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS), St. Louis, MO, Oct. 2009.