Agonist-antagonist Myoneural Interface (AMI)

Song, H., Hsieh, TH., Yeon, S.H. et al. Continuous neural control of a bionic limb restores biomimetic gait after amputation. Nat Med (2024). https://doi.org/10.1038/s41591-024-02994-9

Song H, Israel EA, Gutierrez-Arango S, Teng AC, Srinivasan SS, Freed LE, Herr HM. Agonist-antagonist Muscle Strain in the Residual Limb Preserves Motor Control and Perception after Amputation. Communication Medicine (Lond). 2022 Aug 5;2:97. doi: 0.1038/s43856-022-00162-z PMID35942078; PMC9356003 2022 (Publisher Correction 2022 Sep 26;2:121. doi: 10.1038/s43856-022-00188-3).

Herr HM, Carty MJ. The Agonist-antagonist Myoneural Interface. Tech Orthop. 2021 Dec;36(4):337-344. doi: 10.1097/bto.0000000000000552. PMID: 34866774; PMCID: PMC8630671.

Carty, M.J. and Herr, H.M. The Agonist-Antagonist Myoneural Interface. Hand Clinics. 2021 Aug;37(3):435-445. doi: 10.1016/j.hcl.2021.04.006. https://pubmed.ncbi.nlm.nih.gov/34253316/

Yeon SH, Shu T, Song H, Hsieh TH, Qiao J, Rogers EA, Gutierrez-Arango S, Israel E, Freed LE, Herr HM. Acquisition of Surface EMG Using Flexible and Low-Profile Electrodes for Lower Extremity Neuroprosthetic Control. IEEE Trans Med Robot Bionics. 2021 Aug;3(3):563-572. doi: 10.1109/TMRB.2021.3098952. PMID: 34738079; PMCID: PMC8562690.

Srinivasan SS, Gutierrez-Arango S, Teng AC, Israel E, Song H, Bailey ZK, Carty MJ, Freed LE, Herr HM. Neural interfacing architecture enables enhanced motor control and residual limb functionality postamputation. Proc Natl Acad Sci U S A. 2021 Mar 2;118(9):e2019555118. doi: 10.1073/pnas.2019555118

T. R. Clites, M. J. Carty, S. S. Srinivasan, S. G. Talbot, R. Branemark, H. M. Herr, A caprine model of the agonist-antagonist myoneural interface as implemented at the above- and below-knee amputation levels.: Plastic and Reconstructive Surgery. 2019

S. S. Srinivasan, M. Diaz, M. Carty, H. M. Herr, Towards functional restoration for persons with limb amputation: A dual-stage implementation of regenerative agonist-antagonist myoneural interfaces. Sci. Rep. 9, 1981 (2019).

T. R. Clites, M. J. Carty, J. B. Ullauri, M. E. Carney, L. M. Mooney, J.-F. Duval, S. S. Srinivasan, H. M. Herr, Proprioception from a neurally controlled lower-extremity prosthesis. Sci. Transl. Med. 10, eaap8373 (2018).

S. S. Srinivasan, M. J. Carty, P. W. Calvaresi, T. R. Clites, B. E. Maimon, C. R. Taylor, A. N. Zorzos, H. Herr, On prosthetic control : A regenerative agonist-antagonist myoneural interface, 2, eaan2971 (2017).

T. R. Clites, M. J. Carty, H. M. Herr, in Plastic Surgery Research Council, (2017), p. 119.

T. R. Clites, M. J. Carty, S. Srinivasan, A. N. Zorzos, H. M. Herr, A murine model of a novel surgical architecture for proprioceptive muscle feedback and its potential application to control of advanced limb prostheses., J. Neural Eng. 14, aa614b (2017).

H. M. Herr, T. R. Clites, B. Maimon, A. Zorzos, M. J. Carty, J.-F. Duval, Method And System For Providing Proprioceptive Feedback And Functionality Mitigating Limb Pathology. US Pending Patent 62/276422 (2016).

H. M. Herr, R. R. Riso, K. W. Song, R. J.Casler, M. J. Carty, Peripheral Neural Interface Via Nerve Regeneration to Distal Tissues. US Patent US20160346099 (2016).