Micro-Macro Fluidic Fabrication (MMFF) enables the control of mechanical properties through the design of non-linear lattices embedded within multi-material matrices. At its core it is a hybrid technique that integrates molding, casting, and macro-fluidics. Its workflow allows for the fabrication of complex matrices with geometrical channels injected with polymers of different pre-set mechanical combinations. This novel fabrication technique is implemented in the design and fabrication of a midsole running shoe. The goal is to passively tune material stiffness across surface area in order to absorb the impact force of the user's body weight relative to the ground, and enhance the direction of the foot-strike impulse force relative to the center of body mass.